Streptocid properties and application. What is Streptocid powder used for - benefits and harms

Does Streptocid solution and powder help treat demodicosis? For what other diseases can this antibiotic be used? Although it cannot be called an antibiotic, it is an antiseptic, an antimicrobial drug related to sulfonamides. But in many descriptions it is treated as an "antibiotic". How, according to the instructions, to drink it correctly, how do you put the powder in so as not to harm your health? You will find answers to questions about the drug in this article. We will also talk about the price of a medicine and what analogues it can be replaced with.

general description

Streptocide is a pharmacological antibiotic (sulfanilamide) with big list testimony. It has anti-inflammatory and soothing properties (relieves pain a little). The basis is sulfanilamide (it is also called "white streptocide"). This antibiotic is used for various diseases and inflammations. Judging by the reviews, the tool is loved by the people. This is due to its high efficiency and affordable price (especially in comparison with analogues like Baneocin, whose price is almost three times higher).

Streptocide is available in different forms. Now in pharmacies you can find an antibiotic in the form of:

  • powder,
  • injection solution,
  • tablets,
  • ointments,
  • creams.

Judging by the reviews of experts, the powder form is considered more effective, since it does not contain unnecessary auxiliary components to give consistency. In addition, the powder is considered the most versatile remedy in this group - the solution obtained from it has a very large list of indications (for example, Streptocide cream and ointment have much less indications due to the specifics of their composition and external use).

This is how the original packaging of Streptocid pharmaceutical powder looks in the photo.

How to take the remedy for ticks?

Often doctors prescribe a solution of demodicosis powder. How to take Streptocide if you need to treat demodicosis? The instructions for use are very simple and, judging by the reviews, do not cause difficulties for patients.

First you need to do some preparation. In order for the use of Streptocid from demodicosis to be more effective, you must first clean and warm up the skin of the face affected by the demodex mite. To do this, you can wash your face with hot water, but it’s better to hold your head in a water bath (pour boiling water into a basin or saucepan, lower your head into the steam coming from the water and make a “house” from a towel on top). It is necessary to act carefully - the skin affected by demodicosis is sensitive; make sure that there is no burn, otherwise the pain will be very strong.

As a result of the preparatory procedure, the pores open and mites that love warmth and moisture crawl out (they are small, and you won’t see them with the naked eye). Immediately you need to start processing the skin. To do this, you need a soluble Streptocide - a third of a teaspoon of powder or 2-3 tablets (in the treatment of demodicosis, this amount of Streptocide is more than enough). Dissolve the drug in water until a slurry is formed or simply crush it into dust and apply it in such a dry form to the skin areas damaged by demodicosis.

According to the instructions, it is better to perform the procedure for the treatment of demodicosis with the use of the Streptocid soluble preparation before going to bed, so that by morning the skin will calm down a little. The course of treatment is usually 5-6 days. If no improvement occurs during this time, it means that the infection is too strong and more powerful means are required - consult a doctor and ask for a suitable remedy for demodicosis.

What else does the drug treat, besides demodicosis?

In addition to demodicosis, the antibiotic Streptocid can be used to treat other diseases.

  • Angina and other causes of sore throat.

For diseases of the throat, ointments and creams will not work (according to the instructions they are used only externally), powder or crushed tablets are needed. Antibiotic Streptocid for angina is used very often. Bacteria-affected areas in the throat (those that hurt the most, redden and inflame) are treated with powder. Leave for 10 minutes, and then gargle with a disinfectant solution (for example, a solution of dilute hydrogen peroxide).

The procedure should be repeated as much as possible - at least once an hour. It is best to treat a person with an antibiotic Streptocid in the very first days of the disease, then the inflammation and pain will disappear within a couple of hours. If the disease is more advanced, then the pain and redness will go away for several days.

  • Burns, wounds, pimples, follicles, carbuncles, boils

Streptocide from acne, wounds, burns on the skin is used to disinfect the damaged area, prevent suppuration and inflammation, and dry it. Streptocide from acne, skin wounds and burns should be used within 2-3 days - in the morning and in the evening. If there is already suppuration in the wound, then before pouring streptocide, the sore spot should be treated with diluted hydrogen peroxide.

It is best to prepare a mask called “talker” for the treatment of wounds and acne: take 5 tablets of chloramphenicol, 2 grams of Streptocide powder and a couple of drops of one percent salicylic acid. All these substances can be easily bought at any pharmacy. The price for them is small - within 30 rubles for each ingredient.

  • Trophic ulcers and bedsores

Trophic ulcers and bedsores occur due to malnutrition of the tissue with blood. The reasons for the development of trophic ulcers can be different. They may occur due to arterial insufficiency, diabetes, venous expansion. Bedsores appear when a person is immobilized.

Trophic ulcers and bedsores are an extremely unpleasant and dangerous disease. Experiments with treatment will not work, really proven methods of treatment are needed. Against diseases such as trophic ulcers and bedsores, the use of Streptocid in the form of a compress is suitable.

The instructions for making a compress against trophic ulcers and bedsores are extremely simple: a trophic ulcer or bedsores is treated with hydrogen peroxide, sprinkled with streptocide powder (or a crushed tablet), and a bandage soaked in peroxide solution is applied on top (water with a couple of drops of hydrogen peroxide). Then they wrap the place with the ulcer with cellophane and a warm bandage (a downy scarf is perfect). The compress is changed 2-3 times a day.

  • Stomatitis in adults and children

Doctors often prescribe to patients with stomatitis rinsing the mouth with Streptocid dissolved in water. It disinfects and dries, in addition, reduces inflammation and eliminates pain. The only thing is that powder with water is not the most delicious remedy, and for many it can cause a gag reflex. That is why you can try to replace it with a folk recipe for stomatitis: streptocide, water, honey and a little bit of butter - such a combination for treatment will be more pleasant and convenient for rinsing your mouth.

Is it dangerous to use it?

Sometimes there is information that Streptocide is a strong toxin and poisons a person's orgasm. It is not true. But then where did the opinion come from that it is impossible to treat a person with this antibiotic? The fact is that chemists initially came up with a drug that had the name "red streptocide." It was used in textile industry, but it was found that the new chemical is able to quickly kill microbes. This property interested physicians, and they began to study red streptocide.

At the beginning of the last century, red streptocide was given to people in its pure form. The remedy coped with infections instantly (this saved many people from amputation of limbs). But side effects were catastrophic. It turns out that the original streptocide in the human body is broken down into sulfanilamide (white streptocide) and toxic 1,2,4-triaminobenzene.

As a result, in the 20s of the last century, scientists abandoned the use of red powder in the treatment of people, and began to use only white streptocide, because it is it that has a therapeutic effect and at the same time it does not contain toxins that poison a person. The modern remedy is completely safe for treatment (no more dangerous than hydrogen peroxide), unless, of course, it is taken strictly according to the instructions.

Is it possible to give to children and women in position?

In their reviews, doctors warn that the use of modern Streptocide is safe, but do not forget that this antibiotic has contraindications. For example, the question is often asked: is it possible to take Streptocide during pregnancy? It is possible, but only in the last stages. In the I and II trimesters of pregnancy, the use of this antibiotic is prohibited - you need to select safer analogues that do not contain substances that can harm the fetus.

As for the treatment of children with Streptocid, experts have proven that it is safe for the treatment of children from 1 year old. In this case, it is very important to observe the correct dosage:

  • children under 1 year old should be given 50-100 mg of the drug,
  • a child from 2 to 5 years old is allowed 200-300 mg of medication,
  • children from 6 to 12 years old can be given 300-500 mg of the drug.

What drugs can be substituted?

There was a need to select an analogue similar in properties, instructions for use and price? For some reason, do you want to know what can replace Streptocid's solution or powder? Let's bring comparison table analogues with approximate prices (the Streptocide powder itself costs around 30-35 rubles).

What can replace Streptocid?

Release form

approximate price

Ointment, cream for external use

Berodual

Argosulfan

Cream for external use

Trichopolum

Tablets, solution

Bi-Sept-Pharma

Tablets, cream, ointment

Sulfalen

Tablets

Celederm

Cream, ointment for external use

Liniment Synthomycin

Cream for external use

Please note that all of the listed creams, ointments, solutions and tablets are not complete analogues Streptocide, as they have a different composition and different indications for use. Before you start using them, be sure to consult your doctor (he will determine whether the chosen remedy is suitable). The same applies to the Streptocid powder itself - you should not self-medicate and choose a medicine on your own, focusing only on reviews on the Internet. The drugs are chosen by the doctor based on a confirmed diagnosis and examination of the patient's condition.

Streptocide is a broad-spectrum antibacterial agent characterized by bacteriostatic action against gonococci, streptococci, meningococci, pneumococci, Escherichia coli and other bacteria.

The active substance - Sulfanilamide - has a bacteriostatic effect. The mechanism of action is due to competitive antagonism with PABA and competitive inhibition of the enzyme dihydropteroate synthetase. This leads to disruption of the synthesis of dihydrofolic, and then tetrahydro folic acid and as a result - to disruption of the synthesis nucleic acids.

Active against gram-positive and gram-negative cocci, Escherichia coli, Shigella spp., Vibrio cholerae, Clostridium perfringens, Bacillus anthracis, Corynebacterium diphtheriae, Yersinia pestis, Chlamydia spp., Actinomyces israelii, Toxoplasma gondii.

Streptocid powder has a crystalline structure and white color. Contains the main active ingredient sulfanilamide in the amount of 2 g. The powder is packaged in laminated sachets of 2 g.

When applying the powder to the skin in the area of ​​a wound or inflammatory process, the active ingredient of the drug can be partially absorbed into the systemic circulation. It is evenly distributed in tissues, passes through the blood-brain and placental barrier. It is metabolized mainly in the liver with the formation of inactive decay products that are excreted from the body in the urine.

Indications for use

What helps Streptocide powder? According to the instructions, the drug is prescribed in the following cases:

  • tonsillitis;
  • purulent-inflammatory skin lesions;
  • infected wounds of various etiologies (including ulcers, cracks);
  • furuncle;
  • carbuncle;
  • pyoderma;
  • folliculitis;
  • erysipelas;
  • acne vulgaris (pimples);
  • impetigo;
  • burns (1 and 2 degrees).

Streptocide in the form of a powder is used for the etiotropic treatment of infectious and inflammatory skin diseases caused by microorganisms sensitive to sulfanilamide.

Instructions for use Streptocid, dosage of powder and tablets

The powder is intended for external use. With a shallow skin lesion, Streptocid is applied in a thin layer directly to the area of ​​\u200b\u200bthe pathological process.

For deep wounds, the instruction for the use of Streptocide powder recommends introducing the powder into its cavity, additionally grinding if necessary. The duration of treatment is determined individually.

In bacillary and coccal diseases, the drug is used orally (tablets). The dosage for adults is 500 to 1000 mg 4 to 6 times a day.

In case of wound infections with a purulent complication, for the treatment of infected burns, the introduction of a powder, liniment or Streptocide ointment into the wound is prescribed.

The maximum dose for adults when taken orally: single 2 g, daily - 7 g.

Currently, there is no streptocide in dosage form for internal use, only external. You cannot take it inside.

special instructions

Myelotoxic agents increase the manifestations of hematotoxicity of the drug.

Side effects

The instruction warns of the possibility of developing the following side effects when using Streptocide powder:

  • From the digestive system: nausea, vomiting, diarrhea.
  • From the hemopoietic system: rarely - eosinophilia, thrombocytopenia, leukopenia, hypoprothrombinemia, agranulocytosis.
  • From the CNS and peripheral nervous system: in isolated cases - visual impairment, headache, dizziness, peripheral neuropathy, ataxia.
  • Other: dermal allergic reactions; rarely - nephrotoxic reactions (most likely in patients with impaired renal function); in isolated cases - hypothyroidism.

Contraindications

It is contraindicated to prescribe Streptocide in the following cases:

  • severe renal failure;
  • blood diseases;
  • deficiency of glucose-6-phosphate dehydrogenase;
  • nephrosis;
  • jade;
  • acute porphyria;
  • thyrotoxicosis;
  • 1st and 2nd trimesters of pregnancy;
  • lactation;
  • hypersensitivity to sulfonamides.

Overdose

Overdose symptoms observed when administered orally are nausea, vomiting, dizziness, headache, cyanosis.

It is recommended to wash the stomach with a 2% solution of sodium bicarbonate, inside - a suspension activated carbon, other enterosorbents. Plentiful drinking, intravenous drip administration of sodium bicarbonate are shown. In severe cases - forced diuresis, hemodialysis.

Analogues Streptocid, price in pharmacies

If necessary, you can replace Streptocide with an analogue for the active substance - these are drugs:

  1. Osarcid;
  2. Streptocide white;
  3. Streptocid white soluble;
  4. Streptocide soluble;
  5. Streptocid ointment 10%;
  6. Sulfanilamide;
  7. Streptonitol.

Analogues by ATX code:

  • Streptocid white,
  • Streptocide tablets.

When choosing analogues, it is important to understand that the instructions for using Streptocid powder, price and reviews, do not apply to drugs of similar action. It is important to consult a doctor and not to make an independent replacement of the drug.

Price in Russian pharmacies: Streptocid 2g powder for external use - from 23 to 39 rubles, the cost of ointment 10% 25 g - from 64 rubles, according to 693 pharmacies.

Keep out of the reach of children in the original packaging at a temperature not exceeding 25 °C. Shelf life - 5 years.

Terms of dispensing from pharmacies - without a prescription.

Streptocide is an antimicrobial bacteriostatic drug from the group of sulfonamides, for external and local use.

Release form and composition

Dosage forms of Streptocide:

  • powder for external use: white, crystalline, odorless (2 or 5 g each in a heat-sealed bag made of aluminum foil / paper-based packaging material or combined film materials, in a carton pack of 1, 3, 5, 10 or 20 bags ; for hospitals - in a cardboard box or a plastic bag made of polyethylene food film 50, 100, 200, 300 or 500 bags; 5 or 10 g in a polymer tube sealed with a polymer stopper, or in a glass bottle sealed with a rubber stopper and an aluminum cap, in a carton box 10 or 20 test tubes or vials; for hospitals - in a cardboard box 50, 100, 200, 300 or 500 test tubes or vials; 10 g in a polymer jar with a dispenser, in a carton pack 1 bank);
  • ointment for external and topical use: white or pale yellow (25 g each in an aluminum tube or orange glass jar, in a cardboard box 1 tube or jar);
  • ointment for external use (25, 40 or 50 g in a jar, in a carton pack 1 jar, for hospitals - 64, 49 or 36 jars in a group package; 15, 30 or 40 g in a tube, in a carton pack 1 tube) .

1 dose of powder for external use contains the active substance: sulfanilamide - 2, 5 or 10 g.

Sulfonamides should not be given to children under 2 months of age unless directed by the patient's physician, as sulfonamides can cause serious adverse effects. Sulfonamides are best taken with a full glass of water. Several extra glasses of water should be taken every day unless otherwise directed by your doctor. Drinking extra water will help prevent some of the unwanted effects of sulfonamides.

For patients taking the oral liquid form of this drug. Use a specially marked measuring spoon or other device to accurately measure each dose. The average homemade teaspoon may not contain the correct amount of liquid. . To help clear your infection completely, continue taking this medicine for the full duration of your treatment, even if you start to feel better after a few days. If you stop taking this medicine too soon, your symptoms may return.

100 g of ointment for external and topical use includes:

  • active substance: sulfanilamide - 10 g;
  • additional component: medical vaseline - 90 g.

100 g of ointment for external use contains the active substance: sulfanilamide - 10 g.

Indications for use

Powder
The powder is used as part of the complex therapy of purulent wounds, infected burns (I-II degree) and other purulent-inflammatory processes of soft tissues.

This medicine works best when a constant amount is present in the blood or urine. To maintain a constant value, do not skip any doses. In addition, it is best to take doses evenly spaced day and night. If you need help planning the best times to take your medication, please contact your health care professional.

The dosage of drugs in this class will be different for different patients. Follow your doctor's directions or directions on the label. The following information contains only the average doses of these medicines. If your dose is different, do not change it unless your doctor tells you to.

  • burns (I-II degree);
  • infected wounds of various etiologies;
  • folliculitis;
  • carbuncles, boils;
  • impetigo;
  • acne vulgaris;
  • erysipelas;
  • tonsillitis.

Contraindications

For all forms of release of Streptocide:

  • renal/liver failure;
  • congenital deficiency of glucose-6-phosphate dehydrogenase;
  • anemia;
  • porphyria;
  • azotemia;
  • the period of pregnancy and lactation (breastfeeding);
  • hypersensitivity to sulfonamides.

Optional for powder:

The amount of medicine you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depends on the medical problem you are using the medicine for.

For oral dosage form: Adults and teenagers, 2 to 4 grams for the first dose, then 1 gram every four to six hours. The usual dose is 75 milligrams per kilogram of body weight for the first dose, then 5 mg per kilogram of body weight every six hours or 25 mg per kilogram of body weight every four hours. For bacterial infections: Adults and teenagers, 500 milligrams to 1 gram every six to eight hours. For oral dosage form: For bacterial or protozoal infections: Adults and teenagers, 2 to 4 grams for the first dose, then 1 to 2 grams every eight to twelve hours. The usual dose is 50 to 60 milligrams per kilogram of body weight for the first dose, then 25 to 30 mg per kilogram of body weight every twelve hours. For oral dosage forms: adults and adolescents, 2 to 4 g for the first dose, then 750 to 5 g every four hours; or 1 to 2 grams every six hours. The usual dose is 75 mg/kg body weight for the first dose, then 25 mg/kg body weight every four hours or 5 mg/kg body weight every six hours. Adults and teenagers - 2 to 4 grams for the first dose, then 750 to 5 grams every four hours; or 1 to 2 grams every six hours.

  • Children aged 2 months and older.
  • The dose is based on body weight.
  • The usual dose is 5-25 mg per kilogram of body weight every six hours.
  • Children under 2 months - not recommended.
  • Children under 2 months - Use and dosage should be determined by your doctor.
If you miss a dose of this medicine, take it as soon as possible.
  • chronic heart failure;
  • oppression of bone marrow hematopoiesis;
  • diseases of the hematopoietic system;
  • thyrotoxicosis.

Streptocid should be used with extreme caution in children.

Method of application and dosage

Powder
The powder is used externally, applied directly to the affected areas. Dressings are carried out in 1-2 days.

However, if it is almost the full duration of the next dose, skip the missed dose and go back to your regular dosing schedule. Keep out of the reach of children. Store the medicine in a closed container at room temperature, away from heat, moisture and direct light.

Do not leave outdated medications or medications are no longer needed. The information is for end user use only and may not be sold, redistributed or otherwise used for commercial purposes. Each 5 ml contains 80 mg trimethoprim and 400 mg sulfamethoxazole with 40% propylene glycol, 10% ethanol and 3% diethanolamine; 1% benzyl alcohol and 1% sodium metabisulphite were added as preservatives, water for injection and the pH was adjusted to about 10 with sodium hydroxide.

For adults, the maximum single dose is 5 g, the daily dose is 15 g. For children over 3 years old, the drug is prescribed in a daily dose of 0.3 g.

Ointment
The drug is used topically and externally, lubricating the affected surface or applying gauze pads with ointment applied to it. Dressings are carried out in 1-2 days.

Side effects

During the period of therapy, in the presence of hypersensitivity to the drug, the development of allergic reactions is possible, in which it is necessary to immediately cancel the use of sulfanilamide.

What are the possible side effects of sulfamethoxazole and trimethoprim?

It is a white, light yellow, odorless, bitter compound with a molecular weight of 3 and the following structural formula. It is an almost white, odorless, tasteless compound with a molecular weight of 28 and the following structural formula. Get emergency medical help if you have any of these signs of an allergic reaction: hives; labored breathing; swelling of the face, lips, tongue, or throat.

Call your doctor right away if you have any serious side effects such as. When information on culture and susceptibility is available, these should be considered when selecting or modifying antibiotic therapy. In the absence of such data, local epidemiology and patterns of susceptibility may contribute to the empirical choice of therapy.

External use of streptocid powder for wounds

Early, low birth weight infants may be more likely to develop these reactions because they may be less able to metabolize benzyl alcohol. Hematologic changes indicative of folic acid deficiency may occur in elderly patients. These effects are reversible with folinic acid therapy.

Contraindications to the use of the drug

Careful monitoring of serum potassium is warranted in these patients. The pharmacokinetic parameters for sulfamethoxazole were similar for geriatric subjects and younger adult subjects. General principles of treatment include the administration of intravenous fluids if urine output is low and renal function is normal. Acidification of the urine will increase the renal elimination of trimethoprim. The patient should be monitored with a blood test and appropriate blood chemicals, including electrolytes.

  • various wound infections;
  • suppuration;
  • infected burns;
  • other purulent-inflammatory processes of soft tissues.

Also, streptocide powder was widely used to treat various diseases of the throat, tonsillitis, tonsillitis, stomatitis and inflammation of the oral cavity. To date, the use of streptocide powder for angina and other ENT diseases is not very common, as it has been replaced by more modern and more convenient forms of preparations.

If significant or jaundice occurs, specific therapy should be given for these complications. not effective and only moderately effective in the elimination of trimethoprim and sulfamethoxazole. If signs of bone marrow depression appear, the patient should be given 5 to 15 mg daily until normal life is restored.

Instead of dinner, she went to Boston, where her son, Franklin Jr., was suffering from a sinus problem. The story is, of course, a happy ending with Roosevelt's quick sweep. Fourteen were kept as controls and 12 were treated post-injection with a high dose of dye injected into the gastric tube.

Streptocide is contraindicated in:

  • pregnancy;
  • anemia;
  • kidney disease;
  • renal and hepatic insufficiency;
  • individual intolerance to the substance.

How to use streptocide powder?

For infected wounds, the drug is applied topically, as a powder. Usually streptocide is used when the wound is already inflamed, but in some cases it can be used prophylactically if there is a risk of infection.

All controls died within a few days, while all treated mice survived. This, ironically, was not meant to be. News about a new antibacterial leak. They found that the molecule was composed of two parts: triaminobenzene, which produces a red color, and p-aminobenzenesulfonamide, which is later known as sulfanilamide, which is the active part. The patent problem arose because sulfanilamide was synthesized by the Austrian chemist Paul Gelmo and reported in his doctoral dissertation that it was used as a dye intermediate and its patent expired years before Domagk's discovery.

  1. Streptocide powder is poured directly onto the open wound and onto the skin, about 1-2 centimeters around.
  2. After that, a bandage is applied on top.
  3. It is advisable to change the bandage 2-3 times a day, until the inflammatory process stops.

In addition, a solution of streptocide can be used to wash wounds.

Thus, any number of pharmaceutical companies rushed to produce and improve sulfate preparations. Ironically, the popularity of the drug has brought tragedy as well as benefit. At the time, the regulatory laws in place in the government were only able to take over a product because it was wrong. To be called an elixir, ethanol had to be used.

Tragedy did not stop using sulfa drugs; recognized benefits have generated tremendous growth. American soldiers were taught to sprinkle sulfate powder immediately on any open wound to prevent infection. To do this, each soldier was issued a first aid package designed to be attached to a belt. This bag contained a packet of sulfate powder and a bandage to cover the wound. In addition, sulphate powders and sulphate tablets were the main components of the combat medic kit.

With lacunar angina and tonsillitis, streptocide powder is used to powder the tonsils and inflamed areas of the mucosa. A single dose of the drug is about 500 mg:

  1. The powder is collected with a clean, dry spatula and gently powdered the desired areas of the throat.
  2. After that, it is advisable to try not to swallow for several minutes, and for the next 10 minutes do not drink or eat anything.
  3. Then you can rinse your throat.
  4. The procedure is recommended to be repeated every 4 hours.

Despite its effectiveness, the method is rather inconvenient, so the use of streptocide in the form of a powder for the throat is becoming less common and is being replaced by the use of tablets with a similar active substance, such as Pharyngosept.

With stomatitis and inflammation of the oral cavity, streptocide powder is used both for powdering sores and for rinsing. To prepare the solution, one sachet of powder is poured into a glass of warm water and mixed thoroughly. The same solution can be used to gargle with sore throat instead of powdering the tonsils.

In addition to the above, the use of streptocide powder as one of the components of acne and acne masks is common. In addition, sometimes its solution is used for instillation into the nose with prolonged rhinitis.

Average price online*, 51 rubles. (powder 2g)

Where could I buy:

Instructions for use

Antimicrobial agent, Sulfanilamide (Sulfanilamide, 4-Aminobenzenesulfonamide).

White powdery granules, odorless and tasteless. Solubility: in boiling water - high, in ethanol - poor, in acetone and caustic alkalis - good, in ether, benzene - minimal.

Indications

Streptocide in powder form is active in the treatment of pathologies caused by:

  • gonococci;
  • chlamydia;
  • typhoid-dysenteric bacteria;
  • toxoplasmosis;
  • coli;
  • helminths;
  • meningococci.

Sulfanilamide in powder form is used topically:

  • with infections;
  • purulent manifestations;
  • inflammation;

Streptocide in the form of a powder is used in the treatment of:

  • stomatitis;
  • sore throats;
  • tonsillitis;
  • other ENT diseases.

Dosage and administration

Streptocide for wounds in inflammatory processes on the skin is used as a powder in the form of a therapeutic and prophylactic agent. The powder is locally applied to the wound or skin with a layer of 1-2 mm. In some cases, a bandage is needed from above.

Sulfanilamide in the form of a powder 2 g (1 sachet) is diluted in warm water 250 ml to wash the infected areas.

In ENT diseases, powder 500 mg (single dose) is powdered on inflamed areas of the mucous membrane and tonsils. After the procedure, it is not recommended to swallow for several seconds and it is forbidden to eat and drink for 10 minutes. After the throat is rinsed. Treatment is carried out every 4 hours.

A solution of streptocide is used for rinsing.

Contraindications

Sulfanilamide is not recommended for:

  • renal pathologies;
  • anemia;
  • hepatic failure;
  • hypersensitivity to the main substance;
  • cardiovascular diseases;
  • pathology of the hematopoietic system;
  • thyrotoxicosis;
  • azotemia.

Pregnancy and lactation

Sulfanilamide in the period of systemic absorption tends to penetrate the placenta as quickly as possible and enters the blood of the fetus, can cause intoxication. The safety of streptocide during pregnancy was not confirmed by the study.

Overdose

In case of overdose, sulfanilamide causes the following symptoms:

  • fainting;
  • nausea and vomiting;
  • leukopenia;
  • jaundice;
  • confusion;
  • pain in the abdominal region;
  • violation of visual function;
  • crystalluria.

Therapy: drinking in large quantities, if necessary, gastric lavage.

Side effects

Streptocid can cause some side effects:

  • dizziness;
  • vomit;
  • tachycardia;
  • agranulocytosis;
  • cyanosis;
  • dyspepsia;
  • parasthesia.

Compound

Sulfanilamide 2 g.

Pharmacology and pharmacokinetics

Streptocide acts by competing with para-aminobenzoic acid and suppressing dihydropteroate syntheses, which interrupts the division of dihydrofolic and tetrahydrofolic acids, which prevents the microorganism from multiplying and disrupts the division of their nucleic acids in the body. The substance is active against Gram-positive and Gram-negative microorganisms.

Topical application contributes to the rapid healing of affected areas of soft tissues.

When taken orally, it tends to be absorbed as quickly as possible into the blood from the gastrointestinal tract, and a special concentration is observed after 1 to 2 hours. 50% of the substance is excreted after 8 hours.

Distribution into tissue cells occurs after about 4 hours and some concentration is observed in the cerebrospinal fluid. 95% output naturally via the kidneys through the urinary tract.

Data on carcinogens, mutations are currently absent.

Precautionary measures

When used for a long time, it is recommended to periodically do a peripheral blood test.

Important Notes

During the treatment period, a large amount of drinking is used.

Release form

Streptocide in the form of a powder is available in sachets of 2 g or in a special glass container.

Storage conditions

It is released in pharmacies without a prescription.

Reviews

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Streptocide is a brilliant tool that has existed for more than a decade and was previously considered indispensable for infectious diseases throat. In my home first aid kit, streptocide occupies a very important place, is not the first year and I actively use it not only for the treatment of tonsillitis, wounds and extensive burns. This drug in powder can be used as a unique, cheap, simple, and most importantly effective remedy for acne, or as they are called acne in the people. The treatment is quite affordable and understandable. A bag of powder is diluted in warm water to the state of gruel, which is applied to the affected, inflamed areas. This remedy dries well and kills pathogenic microbes, eliminating the problem. Our family has been using streptocide for three generations and this remedy has never failed. It can be used for large burns, it helps to relieve inflammation and eliminate infection, which can provoke infection and purulent processes. It is very good to gargle with a solution of streptocide and treat the oral cavity during stomatitis. The drug can be mixed with baby cream and applied to children's knees when there are sores from falls. It is worth considering that streptocide has some side effects and therefore it is not worth using it without consulting a doctor. And during the period of taking the drug, you must definitely drink a lot, it is best to drink plain water. The affordable cost of the product can be attributed to another advantage of Streptocide.

Streptocide in the form of a powder, familiar to me since childhood and I still find its use. This remedy helps very well with an inflamed throat and it does not require a lot of money. I get rid of the problem as follows: As soon as the throat starts to hurt, and signs of inflammation were noticed, I take a bag of powder, pour it into a teaspoon and fall asleep in my mouth, but I don’t swallow it, but sort of dissolve it. After the agent has dissolved, it can be swallowed. At the first symptom of a sore throat, I pour a little of this powder into a tablespoon and put it in my mouth. The procedure is carried out three times a day, after which you can not drink any liquids for about half an hour. It is worth noting that the throat becomes healthy very quickly within about two days. The price of Streptocid in a bag is very low and affordable for everyone. I also make a streptocid ointment based on petroleum jelly. Such a tool is good to use for wounds, abrasions, pustules. Vaseline mixed with the medicine is applied to the affected area and, if desired, a bandage is applied, which must be changed periodically. I didn’t notice side effects in myself and my family members, but despite this they exist, so you can consult a doctor for advice, and only then apply the remedy.

It happened that my father burned his leg some time ago. The burn turned out to be quite unpleasant and large, the wound was open. Streptocid once again came to our aid. The drug in the form of a powder is very easy to apply to the affected area and it does not cause discomfort, as it does not sting. If this is a simple wound, then you can apply a bandage on top, with a burn, it is best to leave the lesion open. This is due to the fact that in open form the burn site will not get wet and will heal faster. Within two days, a scab formed on my father's leg and no inflammation or suppuration. Thanks to the bactericidal properties of this inexpensive preparation, we were able to protect the burn site from germs, infection and inflammation. This relieved the father's condition and helped to achieve the healing process very quickly. True, do not forget to treat the wound several times a day. Also, the remedy can be used for pimples, tonsillitis, abrasions, tonsillitis and much more.

* — The average value among several sellers at the time of monitoring, is not a public offer

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All information is presented for educational purposes. Do not self-medicate, it is dangerous! An accurate diagnosis can only be made by a doctor.


Powder "Streptocide" includes in its composition such an active substance as sulfanilamide. This component is a kind of progenitor of a whole group of antibacterial agents. The drug is produced in sachets of 2 g in the form of a white crystalline powder, odorless.

Powder "Streptocide" should be used for inflammatory diseases. With direct interaction, this agent has a pronounced antimicrobial activity. Dosage forms with the active ingredient sulfanilamide are widely known not only in our country, but throughout the world.

The spectrum of action of this drug on the bacterial flora is very wide. When it enters the affected areas of the skin and mucous membranes, it disrupts the synthesis of components and biologically important acids in the cells of microorganisms. Powder "Streptocide" is quite effective against both gram-negative and gram-positive microflora. During use, it has a static effect, prevents the reproduction of pathogenic bacteria. In addition, the presented tool inhibits the vital activity and growth of already developed microbial cells. It comes at the expense of oppression metabolic processes bacteria, as well as antagonistic effects on the mechanism of production of para-aminobenzoic acid. After using the powder, the synthesis of nucleic acids that are necessary for pathogenic microorganisms is stopped, and the production of trihydrate and dihydrate of folic acid is also suppressed. Next comes the paralysis and proliferation of the bacterial cell structure.

During complex therapy, not only Streptocid powder should be used, but also tablets for oral administration. It should be noted that the active ingredient sulfanilamide is very quickly absorbed from the gastrointestinal tract, and after 2 hours it reaches its maximum concentration in the blood. In addition, this component is found in saliva, cerebrospinal fluid, gastric juice, urine, bile, as well as in exudates, transudates and other excretions and secrets of the human body. Streptocide is excreted mainly by the kidneys (about 90-93%).

The most sensitive to treatment with streptocide are such forms of bacterial flora as:

  • shigella (all types);
  • staphylococci;
  • coli;
  • toxoplasma;
  • streptococci;
  • chlamydia;
  • clostridia.

If you combine this medication with other types of antibacterial agents, then the spectrum of its action will expand significantly. "Streptocid" in the form of a powder is most often used in the combined therapy of inflammatory processes that occur on the mucous membranes of the throat and in the oral cavity, as well as on the skin. In addition, this drug is allowed to be used for the treatment of cystitis and infectious intestinal diseases but only in large doses. As a rule, this has a rather adverse effect on the state of the liver and kidneys, and therefore powder medication for the treatment of internal diseases is practically not used. Thus, the presented medication is indicated for the following deviations:

  • lacunar and purulent tonsillitis;
  • purulent infected wounds;
  • erysipelas of the face and lower extremities;
  • burns with secondary infection;
  • stomatitis;
  • gingivitis;
  • gonorrhea (acute and chronic);
  • epidemic cerebrospinal meningitis;
  • pyelitis;
  • colitis;
  • pyoderma, etc.

For the prevention and treatment of wound infections, as well as complications after surgical interventions, purulent sores and burns, the introduction of a sterile powder into the wound (injection) is prescribed. In case of a sore throat, the powder should be powdered on the tonsils on both sides. For adults, this procedure should be carried out every 3 hours at 500 mg, for children from 1 to 12 months - no more than 50 mg per 1 use. A child from 2 to 7 years old "Streptocide" in the form of a powder should be used in an amount of 200 mg (once), and from 7 to 15 years old - 300 mg. The same dosages are recommended to be used for the preparation of an antiviral and antibacterial solution (for rinsing the mouth, etc.) for 1 faceted glass of warm boiled water.

Treatment with "Streptocide" in any form is contraindicated in the presence of pathologies, acute and chronic diseases liver, urinary system and kidneys. In addition, it is not recommended to use this drug even externally for anemia and lesions. thyroid gland if a number of individuals have intolerance to sulfa drugs, diseases of cardio-vascular system, hematopoietic system and pulmonary tuberculosis. If hypersensitivity and the listed contraindications are detected, it is required to immediately abandon the further use of the drug inside and locally.

"Streptocide" for the treatment of purulent and infectious diseases is available not only in powder form, but also in the form of an ointment, as well as in tablet form. As a rule, in severe cases, all the drugs presented are used in combination. This allows you to fight the infection much faster and more efficiently.

After applying "Streptocid" in the form of ointment, powder and tablets, the patient may experience the following side effects:

  • dizziness;
  • allergic reactions;
  • nausea;
  • skin rash;
  • vomit;
  • leukopenia;
  • increase in body temperature;
  • paresthesia;
  • increased heart rate (or the so-called tachycardia);
  • cyanosis;
  • sulfhemoglobinemia;
  • severe headaches;
  • agranulocytosis.

Use the presented preparation "Streptocid" (soluble powder), as well as released in the form of tablets and ointments, should only be used in the dosage that was described in the instructions. Otherwise, an overdose occurs, which is accompanied by the following symptoms: vomiting, intestinal colic, nausea, drowsiness, dizziness, headaches, depression, confusion, fainting, fever, blurred vision, crystalluria and hematuria. If, after such signs, the use of the drug in high doses is not discontinued, this can lead to thrombocytopenia, leukopenia, megaloblastic anemia and jaundice. In case of overdose, the following treatment is recommended: drink plenty of water. If the drug was taken by accident, then gastric lavage is necessary.


Powder, tablets and ointment "Streptocide" should be used with extreme caution in those patients who have impaired renal function. During therapy with this drug, it is recommended to increase the amount of fluid consumed (preferably alkaline, mineral non-carbonated water). At the first manifestation of side effects or hypersensitivity reactions, treatment should be stopped immediately. With long-term therapy with the presented medication, it is desirable to systematically monitor the blood picture, liver and kidney function.

Analogues

  • no analogues

Average price online*, 51 rubles. (powder 2g)

Where could I buy:

  • apteka-ifk.ru
  • apteka.ru

Antimicrobial agent, Sulfanilamide (Sulfanilamide, 4-Aminobenzenesulfonamide).

White powdery granules, odorless and tasteless. Solubility: in boiling water - high, in ethanol - poor, in acetone and caustic alkalis - good, in ether, benzene - minimal.

Streptocide in powder form is active in the treatment of pathologies caused by:

  • gonococci;
  • chlamydia;
  • streptococci;
  • typhoid-dysenteric bacteria;
  • staphylococci;
  • toxoplasmosis;
  • coli;
  • helminths;
  • meningococci.

Sulfanilamide in powder form is used topically:

  • with infections;
  • purulent manifestations;
  • inflammation;
  • furunculosis.

Streptocide in the form of a powder is used in the treatment of:


  • stomatitis;
  • sore throats;
  • tonsillitis;
  • other ENT diseases.

Streptocide for wounds in inflammatory processes on the skin is used as a powder in the form of a therapeutic and prophylactic agent. The powder is locally applied to the wound or skin with a layer of 1-2 mm. In some cases, a bandage is needed from above.

Sulfanilamide in the form of a powder 2 g (1 sachet) is diluted in warm water 250 ml to wash the infected areas.

In ENT diseases, powder 500 mg (single dose) is powdered on inflamed areas of the mucous membrane and tonsils. After the procedure, it is not recommended to swallow for several seconds and it is forbidden to eat and drink for 10 minutes. After the throat is rinsed. Treatment is carried out every 4 hours.

A solution of streptocide is used for rinsing.

  • renal pathologies;
  • anemia;
  • hepatic failure;
  • hypersensitivity to the main substance;
  • cardiovascular diseases;
  • pathology of the hematopoietic system;
  • thyrotoxicosis;
  • azotemia.

Sulfanilamide in the period of systemic absorption tends to penetrate the placenta as quickly as possible and enters the blood of the fetus, can cause intoxication. The safety of streptocide during pregnancy was not confirmed by the study.

In case of overdose, sulfanilamide causes the following symptoms:

  • fainting;
  • nausea and vomiting;
  • leukopenia;
  • jaundice;
  • confusion;
  • pain in the abdominal region;
  • violation of visual function;
  • crystalluria.

Therapy: drinking in large quantities, if necessary, gastric lavage.

Streptocid can cause some side effects:

  • dizziness;
  • vomit;
  • hives;
  • allergic rashes;
  • tachycardia;
  • agranulocytosis;
  • cyanosis;
  • dyspepsia;
  • parasthesia.

Sulfanilamide 2 g.

Streptocide acts by competing with para-aminobenzoic acid and suppressing dihydropteroate syntheses, which interrupts the division of dihydrofolic and tetrahydrofolic acids, which prevents the microorganism from multiplying and disrupts the division of their nucleic acids in the body. The substance is active against Gram-positive and Gram-negative microorganisms.

Topical application contributes to the rapid healing of affected areas of soft tissues.

When taken orally, it tends to be absorbed as quickly as possible into the blood from the gastrointestinal tract, and a special concentration is observed after 1 to 2 hours. 50% of the substance is excreted after 8 hours.

Distribution into tissue cells occurs after about 4 hours and some concentration is observed in the cerebrospinal fluid. 95% is excreted naturally through the kidneys through the urinary tract.

Data on carcinogens, mutations are currently absent.

When used for a long time, it is recommended to periodically do a peripheral blood test.

During the treatment period, a large amount of drinking is used.

Streptocide in the form of a powder is available in sachets of 2 g or in a special glass container.

It is released in pharmacies without a prescription.

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* - The average value among several sellers at the time of monitoring, is not a public offer

Streptocid (sulfanilamide) is an antibacterial drug, the first representative of sulfanilamide drugs.

The drug is active against streptococci, pneumococci, gonococci and other bacteria. Since the accidental discovery of penicillin in 1929, the era of antibiotics has begun in medicine. Streptocide was discovered one of the first.

It is used in the treatment of infectious and inflammatory diseases provoked by bacteria sensitive to the drug. Of the side effects of Streptocide, dyspeptic symptoms (nausea, vomiting, diarrhea), disorders of the hematopoietic system, and dermatological allergic reactions should be distinguished.

Broad-spectrum antibacterial agent.

Can be bought without a doctor's prescription.

How much does Streptocid cost in pharmacies? The average price is at the level of 65 rubles.

In pharmacies you can find ointment and powder. There are also such varieties of the drug as Streptocid white and Streptocide soluble liniment. Since 2008, streptocid tablets have not been produced or sold in Russia.

The active substance is sulfanilamide. Streptocid ointment also contains soft white paraffin as an additional component. The powder contains 0.5 mg of sulfanilamide.

The substance has an antimicrobial effect, is active against gram-positive and negative cocci. Applying the powder to damaged skin accelerates wound healing, helps erosions to epithelialize faster. The mechanism of action is based on the connection of compounds with para-aminobenzoic acid, which is necessary for the vital activity of bacteria.

Due to the similarity with this acid, sulfonamides penetrate into the protoplasm of bacteria, replace the substrate, and block the enzyme system. There is a violation of metabolic processes, microbes stop growing and multiplying due to the lack of folic acid intake. Sulfanilamide is active, rapidly absorbed from the gastrointestinal tract. It reaches its maximum concentration in a couple of hours, being found in the blood.

Four hours after taking Streptocid is found in cerebrospinal fluid, saliva, gastric juice, bile, urine. Part of the molecule under the action of enzymes becomes acetoform, which reduces the antimicrobial activity of the agent. This form is found in 10-20% concentration in the blood, in the urine - up to 50%. In eight hours, 50% of the drug is excreted by the kidneys.

The drug is used in the treatment of the following infectious and inflammatory diseases, which are caused by microorganisms sensitive to the action of the drug:

  • impetigo;
  • carbuncles;
  • erysipelas;
  • pyelitis;
  • cystitis;
  • sore throats;
  • enterocolitis;
  • boils;
  • infectious diseases of the mucous membranes and skin.

Also, this remedy is used in the complex therapy of infected burns (I–II stage), purulent wounds and other purulent-inflammatory processes of the skin.

Streptocid tablets are prescribed for infectious diseases of the skin, upper respiratory tract, respiratory and urinary tract, wound infections.

Severe renal failure, blood diseases, deficiency of glucose-6-phosphate dehydrogenase, nephrosis, nephritis, acute porphyria, thyrotoxicosis, I and II trimesters of pregnancy, lactation, hypersensitivity to sulfonamides.

The contraindications to the drug indicate that Streptocid during pregnancy and lactation is prohibited. The active substance of the drug quickly passes through the placental barrier and is found in the blood of the fetus. In addition, it can cause toxic effects.

At breastfeeding the drug can provoke kernicterus in infants.

As indicated in the instructions for use, Streptocide powder can be applied externally to the damaged surface of the skin or blown into deep wounds. Also, in a mixture with Sulfathiazole, Benzylpenicillin and Ephedrine, Streptocide is used for nasal retraction in acute rhinitis.

If the wound is deep, then Streptocide powder is blown directly into it. At the same time, 5-15 g of powder is taken for one injection, depending on the size of the wound. After blowing the powder, the wound is usually covered with a bandage. The powder is blown in 1-4 times a day, depending on the intensity of the discharge from the wound, guided by the rule: the more the wound gets wet, the more often the powder should be blown into it. Powder is applied to wounds until they begin to heal or until the release of pus or inflammatory fluid from the wound surface stops.

One of the effective remedies in the fight against acne is Streptocid. It is a good antiseptic and destroys pathogenic microflora. For the treatment of skin rashes, streptocid ointment is most often used. The drug in the form of a powder is more suitable for the manufacture of lotions and masks. Before using the ointment, wash your face and wipe it with tincture of calendula.

Then apply ointment to each pimple (do this twice a day for 2 weeks). You can also use tablets: crush 20 pieces into powder and mix with aloe juice to the consistency of sour cream, add a couple of drops of iodine. Apply this mixture on your pimples at night and wash off with plain water in the morning. If the use of Streptocid does not help, then it is necessary to consult a doctor so that he can identify the cause of acne (this may be a hormonal surge, clogged pores, or disruption of the digestive tract).

When using the drug, allergic reactions are possible, in addition, the following side effects are observed: headache, paresthesia, nausea, dyspepsia, agranulocytosis, cyanosis, dizziness, tachycardia, vomiting, leukopenia, crystalluria.

Tablets can also cause diarrhea, and in rare cases, nephrotoxic reactions, thrombocytopenia, hypoprothrombinemia, eosinophilia, visual impairment, peripheral neuritis, hypothyroidism, ataxia.

Overdose symptoms are as follows: headache, vomiting, nausea, cyanosis, dizziness.

In case of overdose, symptomatic therapy should be carried out.

In the treatment of patients with pathologies of kidney function, Streptocide is used with caution. The amount of fluid consumed during the treatment period should be increased.

When treating with a drug or an analogue of Streptocid, it must be borne in mind that novocaine and other drugs with a similar chemical structure containing a para-aminobenzoic acid residue may exhibit an antisulfanilamide effect.

We suggest that you read the reviews of people who used the drug Streptocid:

  1. Victoria. Streptocide is always in my first aid kit. I have two children, they often have abrasions and wounds after playing outdoors. Streptocide should be sprinkled on wounds so that they do not fester. You can also dilute the streptocide with water and wipe the walls with mold, it perfectly removes.
  2. Andrew. This is a proven tool. I often go camping and like to take this powder with me. It heals open wounds well and disinfects them, which is very important when there is nothing else at hand. But the problem is that finding this drug is not so easy. You run half the city before you buy. This has become a rarity, surprised, as an excellent tool
  3. Lera. I remember my mother in childhood treated our knees first with hydrogen peroxide, then poured streptocide powder. Vavki healed faster, they didn’t leave terrible scars. They say he is now sold in the form of a powder. I used to remember that it was in dark bottles, but now they say that it is in bags. By the way, he did not pinch when he hit the wound, which is very important for children. So I still recommend it to everyone.

By structure, active active ingredient and pharmacological action, the following analogues of Streptocid are distinguished - sulfanilamide preparations:

  • Streptonitol;
  • Osarcid;
  • Sulfanilamide;
  • Streptocide soluble;
  • Sunorfe ointment (contains, in addition to sulfanilamide, eucalyptus oil, camphor, ephedrine hydrochloride, sulfadimezin, norsulfazol - treats acute and chronic rhinitis).

Before buying an analogue, consult your doctor.

Keep out of the reach of children at a temperature not exceeding 25 °C. The shelf life of the liniment is 4 years, the powder for external use, ointments and tablets is 5 years.

is an antimicrobial medicinal product groups

sulfonamides

for external and local use. Streptocid is used to treat infectious and inflammatory diseases of the skin and mucous membranes, such as tonsillitis, infected wounds, burns,

folliculitisfuruncles

impetigorozh

Strictly following the letter of the rules, it must be assumed that the funds listed above with different names are varieties of Streptocide. However, the above different names belong to the same drug - Streptocide. Different names of the same medicine are due to the fact that some pharmaceutical factories produce medicine under historically established names. In fact, all Streptocides, regardless of the name, contain the same active substance and are produced in the same dosage forms, so there is no difference between them, except for the names. Given this state of affairs, in the future text of the article we will use the same name "Streptocid" for all drugs produced under different historical names.

Streptocide is currently available in Russia in the following dosage forms:

  • Ointment 10%
  • Liniment 5% for external and local use;
  • Powder for external use.

Under the name "Streptocide" a powder and ointment are produced, under the name "Streptocide ointment", respectively, an ointment, and under the name "Soluble Streptocide" - liniment.

In the form of tablets Streptocide is not currently produced in Russia and Belarus, although such a dosage form existed in the past. However, in Ukraine, Streptocid is still available in tablets for oral administration. Also currently does not exist in Russia and Belarus, but in the past it was produced "Streptocid soluble" in powder form for preparing solutions for intravenous administration. Streptocid in tablets and in the form of intravenous injections was used to treat tonsillitis, erysipelas, cystitis, pyelitis, enterocolitis, wound infection and other infectious and inflammatory diseases of various organs caused by pathogenic microorganisms. Streptocide for oral and intravenous administration was no longer produced and used, since more effective drugs appeared. medicines(antibiotics and other, newer and more effective drugs of the sulfonamide group). Accordingly, currently in Russia and Belarus, Streptocide is produced and used only in forms for external and local use, and in Ukraine the drug continues to be used in dosage forms for external use and for oral administration.

Given the fact that the forms of Streptocide for oral administration are outdated, and in Ukraine they are produced mostly by inertia, we will consider various aspects of using only ointment, liniment and powder for external use. And we will not give various aspects of the use of Streptocid tablets, since this is impractical. After all, Streptocide tablets are too outdated, because in order to achieve the desired therapeutic effect, they must be taken in very high doses, which leads to a high risk of side effects. Currently, other drugs of the sulfonamide group are being produced, which, compared with Streptocide, are much more effective and with fewer side effects (for example, Biseptol, Sulfamethoxazole, Sulfadimethoxine, etc.).

All currently existing dosage forms Streptocide as an active substance contain sulfanilamide. Moreover, the ointment and powder contain the usual sulfanilamide, and the liniment contains a soluble form of sulfanilamide, which is also called mesulfamide.

Powder for external use contains only the active substance itself - sulfanilamide, and does not contain auxiliary components, unlike ointment and liniment. The ointment also contains sulfanilamide in the amount of 10 g per 100 g of the finished product, and liniment - 5 g per 100 g of the finished product. Accordingly, Streptocide ointment has a 10% concentration, and liniment - 5%. Streptocide ointment contains medical vaseline as auxiliary components, and liniment contains glycerin, purified water and an emulsifier (Lanette SX, Neowax SX).

Streptocid powder is available in heat-sealed bags of 2 g or 5 g, and is a white powdery mass. Ointment 10% is available in aluminum tubes or dark glass jars with a volume of 25 g or 50 g, and is a homogeneous thick mass of white or light yellow color. Liniment 5% is available in aluminum tubes or dark glass jars with a volume of 30 g, and is a homogeneous thin mass of white or white with a creamy tint.

Rp.: Streptocidi 10% unguentum

In the recipe after the abbreviation "Rp." followed by the name of the drug Latin"Streptocidi", followed by its dosage form and concentration (also in Latin): "10% unguentum". On the second line after the abbreviation "S." indicates how to use the prescribed remedy. The second line of the prescription is an indication for the patient.

Recipe for Streptocide liniment is written as follows:

Rp.: Streptocidi 5% linimentum

S. Lubricate wounds 3-4 times a day.

In the prescription, the first line indicates in Latin the name of the drug (Streptocidi), its dosage form (linimentum) and concentration (5%). The second line tells the patient how to use the medicine prescribed by the doctor.

Recipe for Streptocide Powder is written as follows:

Rp.: Streptocidi pulvis 5 g

S. Powder wounds 3 to 4 times a day.

In the prescription, in the first line, the doctor in Latin indicates the name and dosage form of the drug (Streptocidi pulvis - Streptocide powder), and in the second line - a brief prescription for the patient on how to use the remedy.

Streptocide has a detrimental effect on gram-positive and gram-negative cocci (spherical bacteria), such as streptococci, staphylococci, pneumococci, meningococci, gonococci, enterococci, etc. In addition, Streptocide is detrimental to the following microorganisms:

  • Escherichia coli;
  • Shigella spp.;
  • Vibrio cholerae;
  • Clostridium perfringens;
  • Bacillus anthracis;
  • Corynebacterium diphtheriae;
  • Yersinia pestis;
  • Chlamydia spp.;
  • Actinomyces israeli;
  • Toxoplasma gondii.

Accordingly, all dosage forms of Streptocide can be used to treat infectious and inflammatory diseases of the skin or mucous membranes of the mouth and nose caused by any of the above microbes.

Since the drug has an antimicrobial effect, it indirectly also has an anti-inflammatory effect due to the death of microbes that provoked an infectious and inflammatory process.

In addition to anti-inflammatory and antimicrobial action, Streptocide promotes faster healing of wounds on the skin.

So, Streptocid powder, Streptocid ointment and Streptocid (soluble) liniment are indicated for use as part of complex therapy for the treatment of the following diseases:

  • Tonsillitis;
  • Infected wounds of the skin (festering wounds);
  • Burns of I-II degrees;
  • Ulcers on the skin of various origins (including trophic ones);
  • Erysipelas;
  • Cracks in the skin;
  • Purulent-inflammatory skin diseases, such as folliculitis, boils, carbuncles, acne vulgaris, impetigo, pyoderma, etc.

The powder is applied to the damaged surface of the skin by powdering, that is, first a little powder is poured onto the gauze, after which the surface of the wound is “powdered” with this gauze. You can also gently pour the powder directly from the bag onto the surface of the wound. But at the same time, you should try to evenly distribute the powder over the surface of the wound. After applying the powder to the damaged surface, it can be covered from above with a gauze cloth, dressed or left uncovered. For a single application to the wound, take 2-5 g of powder, depending on the size of the damage.

The powder can be applied to the wound surface 3-4 times a day. In this case, the frequency of application of the powder is determined by the course of the infectious-inflammatory process. For example, if the wound is weeping, with abundant discharge, then powder is often sprinkled on its surface, up to 4 times a day. If the wound is dry, then it can be treated with Streptocid powder only 1-2 times a day. In such a situation, it is recommended to apply Streptocide powder 1 time per day if the wound is then closed with a bandage, and 2 times a day if the wound is left open.

If the wound is deep, then Streptocide powder is blown directly into it. At the same time, 5-15 g of powder is taken for one injection, depending on the size of the wound. After blowing the powder, the wound is usually covered with a bandage. The powder is blown in 1-4 times a day, depending on the intensity of the discharge from the wound, guided by the rule: the more the wound gets wet, the more often the powder should be blown into it.

Powder is applied to wounds until they begin to heal or until the release of pus or inflammatory fluid from the wound surface stops.

In acute rhinitis, Streptocide powder is mixed with Sulfathiazole, Benzylpenicillin and Ephedrine, and is drawn in by the nose when inhaling. This powder mixture can be used for several days (5 - 7) to treat the common cold. In this case, the mixture is drawn into the nose several times a day, carrying out this procedure when an abundant discharge from the nose reappears.

The wound treated with ointment or liniment is closed with a gauze bandage, which is changed once every 1 to 2 days. Ointment or liniment is applied until pus or inflammatory fluid ceases to stand out from the wound, and it begins to heal.

Ointment or liniment is applied to the mucous membranes 2-3 times a day at regular intervals until the wound heals, or until the severity of the inflammatory process decreases.

For extensive wound surfaces, it is necessary to take into account that the maximum daily dosage of preparations for the treatment of lesions is 6 g of sulfanilamide (for adults). This amount of sulfanilamide (6 g) corresponds to 120 g of liniment or 60 g of Streptocide ointment. The maximum daily dosage of Streptocid drugs for external and local use for children 5-12 years old is 3 g of sulfanilamide (which corresponds to 60 g of liniment or 30 g of ointment), for children 1-5 years old - 1.8 g of sulfanilamide (which corresponds to 36 g of liniment or 18 g of ointment), and for children under 1 year old - 0.6 g of sulfanilamide (which corresponds to 12 g of liniment or 6 g of ointment). This daily dosage limit means that within 24 hours for the treatment of wounds and inflammatory elements, you can use no more than 120 g of liniment or 60 g of ointment for adults and adolescents over 12 years old, no more than 60 g of liniment or 30 g of ointment for children 5 - 12 years, no more than 36 g of liniment or 18 g of ointment for children 1-5 years old and no more than 12 g of liniment or 6 g of ointment for children under one year old. The limitation of the daily dosage for the treatment of extensive wound surfaces is due to the fact that the active substance from damaged skin and mucous membranes is easily absorbed into the bloodstream, and can have a systemic effect and provoke the development of severe systemic side effects.

On average, the course of application of Streptocide ointment or liniment is 10 to 14 days, however, if necessary and on the advice of a doctor, you can extend the use of the drug. Without the recommendation of a doctor, do not use liniment or ointment for more than two weeks in a row.

With the development of allergic reactions, the use of Streptocid should be immediately discontinued.

During the entire period of application of the ointment, powder or liniment of Streptocid, it is necessary to drink a large amount of alkaline liquids (for example, alkaline mineral waters, such as Borjomi, Essentuki 4, Slavyanovskaya, etc.).

If an ointment, liniment or powder is accidentally ingested (for example, by accidental swallowing), the stomach should be washed out as soon as possible, after which alkaline liquids should be drunk abundantly during the day (for example, mineral water Borjomi, Essentuki 4, Smirnovskaya, Nabeglavi, Luzhanskaya, etc. .d.).

With prolonged use of ointment, powder or liniment, Streptocide must be taken regularly general analysis blood, as well as monitor the condition of the liver and kidneys.

An overdose is manifested by the following symptoms:

  • Headache;
  • Nausea;
  • Vomit;
  • The phenomena of dyspepsia (heartburn, belching, flatulence, etc.);
  • intestinal colic;
  • Dizziness;
  • Drowsiness;
  • Depression;
  • fainting;
  • confusion;
  • visual impairment;
  • Fever;
  • Hematuria (blood in the urine);
  • Leukopenia (decrease in the total number of white blood cells in the blood);
  • Agranulocytosis (disappearance of neutrophils, basophils and eosinophils from the blood);
  • Thrombocytopenia (decrease in the total number of platelets in the blood) - observed only with prolonged overdose;
  • Megaloblastic anemia - observed only with prolonged overdose;
  • Jaundice - observed only with prolonged overdose.

For the treatment of an overdose, it is necessary to cancel the use of Streptocide and drink alkaline drinks abundantly for several days.

(for example, Borjomi, Essentuki 4, Smirnovskaya, Nabeglavi, Luzhanskaya, etc.). Drink alkaline mineral water needed until all the symptoms of an overdose have passed.

Interaction with other drugs Ointment, liniment and powder Streptocid, when used to treat large wound surfaces or when used for a long time, when sulfanilamide can be absorbed into the systemic circulation, can increase the toxic side effects on the blood system of any other drugs that have hematotoxicity.

In addition, if Novocain and Streptocid are used one after another, this reduces the effectiveness of the latter. Therefore, if necessary, the simultaneous use of Novocaine and Streptocide should be maintained at least half an hour between their use. With other external agents, ointment, liniment and Streptocid powder do not interact with significant effects.

Against the background of the use of ointment, liniment or Streptocid powder, it is recommended to stop using the following drugs:

  • Digitoxin;
  • Isoprenaline;
  • Caffeine;
  • Phenylephrine;
  • Phenobarbital;
  • Adrenalin;
  • Hydrochloric acid.

The safest for use in children is Streptocide liniment. And ointment and powder, compared to liniment, are more dangerous because they contain large quantity active substance. Liniment can be used without fear for children from the age of three months, and ointment and powder - with three years of age. For children from birth to three months, liniment can also be used, but with caution, in minimal dosages and only under medical supervision. Accordingly, the ointment and powder can also be used to treat infectious and inflammatory diseases of the skin and mucous membranes of the mouth and nose in children under 3 years of age, but with caution and under the supervision of a doctor.

When used in children, it is necessary to strictly adhere to the maximum allowable dosages and terms of use in order to avoid overdose.

It is undesirable to use Streptocid ointment, liniment and powder for treating large surfaces in children so that the active substance is not absorbed into the bloodstream and does not cause systemic side effects.

With the appearance of systemic side effects, it is necessary to stop the use of Streptocid in children.

Ointment, powder and liniment in children are used in the same way as in adults.

To prepare the talker, mix 50 ml of a 2% solution of salicylic acid, 50 ml of boric acid, 7 g of Streptocid powder and 7 g of precipitated sulfur. All components are thoroughly mixed, and the finished composition is stored in a dark glass jar.

The talker is applied to the affected areas of the skin once a day in the evening, before going to bed, after cleansing the skin. 5 minutes after applying the talker, you can lubricate your face with a moisturizer.

Chatterbox with Streptocid can be used both for the treatment and for the prevention of acne, acne and pustular skin rashes. However, you can not use the talker for a long period of time without interruption. It is recommended to use one portion of the manufactured mash, and then take a break for a month, after which you can again conduct a course of therapy with a self-made remedy.

Streptocide and Salicylic acid Streptocide and salicylic acid in the form of a mixture are used to treat and prevent acne, acne and pustular lesions of the skin. Streptocid destroys pathogenic microbes that cause an infectious and inflammatory process on the skin, and salicylic acid reduces the production of sebum and promotes wound healing. Accordingly, a mixture of Streptocid with salicylic acid is effective tool for the treatment of acne and acne.

To prepare the composition, add 5 g of Streptocide powder to 50 ml of 2% salicylic acid, mix thoroughly and place in a dark glass jar for storage. This composition should be applied to previously cleansed skin in the evening, before going to bed, once a day.

A solution of Streptocide in salicylic acid should be used in courses lasting up to one month. After the end of the course of therapy, you need to take a break (at least a month), after which you can use the solution again.

To prepare the talker, you need to mix 30 ml of salicylic acid, 2 g of Streptocid powder and 4 Levomycetin tablets powdered into powder. The finished composition is placed in a dark glass jar and stored for no longer than 1 - 2 months.

The talker is applied to the affected areas of the skin once a day in the evening, before going to bed, after preliminary cleansing of the skin.

Streptocide from the throat (with sore throat) Currently, Streptocide powder is used to treat pain and inflammation in the throat (for example, pharyngitis, ulcers, etc.) and tonsillitis. In the past, Streptocid tablets for oral administration were also used to treat angina, but they are not currently used, since there are more effective and safer means, including those from the group of sulfanilamide drugs, such as Biseptol, Sulfadimetoksin, etc.

Streptocid powder for the treatment of sore throat can be used in three ways - they are sprinkled with tonsils, dissolved in the mouth or gargled. For sprinkling, a small amount of powder is taken and applied to the tonsils (it is convenient to do this with an ordinary cotton swab), after which you should try not to swallow saliva, eat or drink for 10 minutes so that the drug remains on the mucous membranes. After 10 minutes, the powder is spit out and the throat is gargled with any disinfectant solution, for example, chlorhexidine, furacilin, etc. Such treatment of the throat (sprinkling with Streptocide powder + gargling with a disinfectant solution) is carried out every 2 hours.

For resorption in the mouth, you can use pure Streptocide powder or mixed with honey. Pure powder is poured into a teaspoon (about 1/4 - 1/2 spoon), then licked off and held in the mouth until completely dissolved. Unfortunately, resorption of pure Streptocide powder brings discomfort because the drug is bitter. Therefore, to eliminate an unpleasant bitter taste, Streptocid powder is often mixed with honey. The resulting mixture is absorbed as long as possible in the oral cavity. After complete resorption of pure powder or mixed with honey, it is necessary to refrain from eating and drinking for 20-30 minutes so that the medicine stays longer on the mucous membranes. To treat a sore throat, it is necessary to dissolve a mixture of honey with Streptocide or pure powder 2 to 3 times a day.

In addition, you can dissolve Streptocide powder in warm water, and gargle with the resulting solution. To prepare a solution for rinsing, take 2 g of powder in a glass of warm water. Rinsing is done every 2 hours.

More about angina

Streptocide ointment or liniment for the treatment of acne and acne is recommended to simply be applied to the skin as a cream 1 to 2 times a day after cleansing the skin. The ointment or liniment is left on the skin overnight or for several hours if the drug was applied during the daytime. If there are few acne or blackheads, then these funds can be applied pointwise, directly on the rash.

And the powder immediately after washing just powder the skin. To do this, after washing, the skin is allowed to dry so that it does not become wet, but slightly moist, after which Streptocide powder is collected on the fingertips, and with patting movements it is gently distributed over the entire problem area of ​​​​the skin. Dusting with Streptocide powder is performed 1 time per day in the evening, before going to bed. The applied powder is left overnight and washed off in the morning.

Streptocid quickly eliminates redness, reduces swelling and stops the inflammatory process. Thanks to this action, pimples and blackheads present on the skin are resolved within a short period of time, and new rashes do not appear.

The drug is used in courses lasting 2 to 4 weeks, after which they take a break for a month and, if necessary, repeat the course of treatment. Streptocid can also be used sporadically when skin rashes are already mostly cured, but sometimes single pimples or blackheads appear. In such cases, the ointment, powder or liniment is used for several days to quickly eliminate the rashes that have appeared.

In addition, Streptocide for the treatment of acne and acne can be used not in its pure form, but in the form of a mash prepared on the basis of salicylic acid. The recipe for the preparation and rules for using such talkers are given in the relevant sections. However, the effectiveness of the talker and Streptocid in its pure form for the treatment of acne and blackheads is approximately the same.

More about acne

The powder is poured directly onto the wound or into the wound if it is deep, after which it is covered with a gauze or bandage. Ointment or liniment can be applied either directly to the wound, or applied to gauze and cover the wound surface with it. After applying a powder, ointment or liniment to the wound, it is recommended to cover the wound surface with a gauze bandage. Powder, ointment or liniment is applied to the wound 1-4 times a day for 10-14 days.

Before applying the powder, liniment or ointment Streptocide, the wound should be washed with hydrogen peroxide or another disinfectant (for example, a solution of potassium permanganate, furacilin, etc.).

More about wounds

Ointment, liniment and powder are most often used as side effects provoke allergic reactions on the skin (urticaria, etc.) or dermatitis (rash, itching, burning of the skin). However, with prolonged use of an ointment, liniment or powder in large doses or for treating large wound surfaces, the active substance of Streptocid may be absorbed into the bloodstream with the development of systemic side effects, such as:

  • Headache;
  • Dizziness;
  • Nausea;
  • Vomit;
  • Dyspeptic phenomena (belching, heartburn, diarrhea, constipation, etc.);
  • Cyanosis (blanching or "blue" of the skin);
  • Crystalluria (salt crystals in the urine);
  • Impaired kidney function;
  • thyrotoxicosis ( elevated level thyroid hormones in the blood)
  • Leukopenia (decrease in the total number of leukocytes in the blood below normal);
  • Agranulocytosis (complete absence of neutrophils, eosins and basophils in the blood);
  • Thrombocytopenia (lower than normal levels of platelets in the blood);
  • Hypoprothrombinemia (the level of prothrombin in the blood is below normal).

With the development of side effects of Streptocid, it is necessary to stop using the drug and consult a doctor.

  • Individual hypersensitivity or allergic reactions to any components of the drug or to other drugs of the sulfonamide group;
  • Anemia;
  • Chronic heart failure;
  • Hematopoietic disorders;
  • thyrotoxicosis;
  • kidney failure;
  • Liver failure;
  • Nephrosis;
  • Nephritis;
  • Porfiria;
  • Azotemia - an increased level of nitrogenous compounds (urea, creatinine, etc.) in the blood;
  • Deficiency of the enzyme glucose-6-phosphate dehydrogenase;
  • The period of pregnancy and breastfeeding.

So, the following drugs are analogues of Streptocide in terms of therapeutic action:

  • Argedin cream for external use;
  • Argosulfan cream for external use;
  • Dermazin cream for external use;
  • Turmanidze ointment for external and local use;
  • Mafenida acetate ointment for external use;
  • Sulfadimezin tablets for oral administration;
  • Sulfargin ointment for external use;
  • Ebermin ointment for external use;
  • Etazol tablets, solution for injection, granules for suspension for oral administration.

The reviews also indicate that Streptocide powder perfectly heals and disinfects a variety of wounds on the surface of the skin (for example, abrasions, cuts, non-healing umbilical wounds, calluses, surgical incisions after removal of warts, moles, etc.). Moreover, if the wounds are processed within short term after their appearance, a crust forms on them very quickly, and healing proceeds without complications, suppuration, weeping and without scarring. If the wounds fester, get wet and do not heal for a long time, then sprinkling them with Streptocide powder leads to a rapid cessation of the inflammatory process, the formation of a crust and subsequent healing.

The reviews also indicate that Streptocide powder is an excellent, highly effective treatment for acne and blackheads.

About the ointment and liniment of Streptocide, the reviews indicate that these are excellent means for treating various wound surfaces on the skin, leading to rapid crusting and healing.

  • Powder 2 g, 1 sachet - 15 - 60 rubles;
  • Powder 5 g, 1 sachet - 30 - 72 rubles;
  • Ointment 10%, tube or jar 25 g - 50 - 80 rubles;
  • Liniment 5%, tube or jar 30 g - 71 - 98 rubles.

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